製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-ARAIIREGSLEGS
    • 領域644 to 656

関連製品

特性

Our Abpromise guarantee covers the use of ab45561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Pericentrin 1 antibody (ab19044)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • 85 kDa nucleoporin
    • FLJ12549
    • FROUNT
    • Frount protein
    • Nuclear pore complex protein nucleoporin 85 kDa
    • nuclear pore complex protein nucleoporin Nup75
    • Nuclear pore complex protein Nup85
    • Nucleoporin 85
    • Nucleoporin 85kDa
    • Nucleoporin nucleoporin 85kDa
    • Nucleoporin Nup75
    • Nucleoporin NUP85
    • nucleoporin, 75-KD
    • Nucleoporin85
    • Nup 75
    • NUP 85
    • Nup75
    • nup85
    • NUP85_HUMAN
    • PCN
    • PCNT
    • PCNT 1
    • PCNT, formerly
    • PCNT1
    • Pericentrin
    • Pericentrin, formerly
    • Pericentrin-1
    • Pericentrin1
    see all
  • 機能Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.
  • 配列類似性Belongs to the nucleoporin Nup85 family.
  • 細胞内局在Nucleus > nuclear pore complex. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Cytoplasm. Nucleus membrane. During mitosis, localizes to the kinetochores and spindle poles. Upon CCl2 stimulation translocates from the cytoplasm to the membrane and colocalizes with CCR2 at the front of migrating cells.
  • Information by UniProt

Human Pericentrin 1 peptide (ab45561) 使用論文

ab45561 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"