製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      DLEKNYPTPRTSR-C
    • 領域
      2 to 14

関連製品

特性

Our Abpromise guarantee covers the use of ab22941 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-PAX5 antibody (ab2935)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • B cell lineage specific activator
    • B cell lineage specific activator protein
    • B cell specific activator protein
    • B cell specific transcription factor
    • B-cell-specific transcription factor
    • BSAP
    • EBB-1
    • KLP
    • Paired box 5
    • Paired box gene 5
    • Paired box gene 5 (B cell lineage specific activator protein)
    • Paired box gene 5 (B cell lineage specific activator)
    • Paired box homeotic gene 5
    • Paired box protein Pax 5
    • Paired box protein Pax-5
    • Paired domain gene 5
    • PAX 5
    • PAX5
    • PAX5_HUMAN
    • Transcription factor PAX 5
    see all
  • 機能
    May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
  • 関連疾患
    A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.
    Leukemia, acute lymphoblastic, 3
  • 配列類似性
    Contains 1 paired domain.
  • 発生段階
    Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
  • 翻訳後修飾
    O-glycosylated.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

参考文献

ab22941 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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