製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-DVRQWATSSLSWL
    • 領域424 to 436

関連製品

特性

Our Abpromise guarantee covers the use of ab23156 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-ORC4L antibody - ChIP Grade (ab9641)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Origin recognition complex, subunit 4, S. cerevisiae, homolog of
    • FLJ46668
    • HSORC4
    • ORC 4
    • ORC 4L
    • ORC 4P
    • ORC4
    • ORC4_HUMAN
    • ORC4L
    • ORC4L protein
    • ORC4P
    • Origin recognition complex subunit 4
    • Origin recognition complex subunit 4 (yeast homolog) like
    • Origin recognition complex subunit 4 like
    • Origin recognition complex subunit 4 like (yeast)
    • origin recognition complex, subunit 4 homolog
    • Origin recognition complex, subunit 4, S. cerevisiae, homolog-like
    see all
  • 機能Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  • 関連疾患Defects in ORC4 are the cause of Meier-Gorlin syndrome type 2 (MGORS2) [MIM:613800]. MGORS2 is a syndrome characterized by bilateral microtia, aplasia/hypoplasia of the patellae, and severe intrauterine and postnatal growth retardation with short stature and poor weight gain. Additional clinical findings include anomalies of cranial sutures, microcephaly, apparently low-set and simple ears, microstomia, full lips, highly arched or cleft palate, micrognathia, genitourinary tract anomalies, and various skeletal anomalies. While almost all cases have primordial dwarfism with substantial prenatal and postnatal growth retardation, not all cases have microcephaly, and microtia and absent/hypoplastic patella are absent in some. Despite the presence of microcephaly, intellect is usually normal.
  • 配列類似性Belongs to the ORC4 family.
  • 細胞内局在Nucleus.
  • Information by UniProt

Human ORC4L peptide (ab23156) 使用論文

ab23156 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"