製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-SWARGPPKFESVP
    • 領域962 to 974

関連製品

特性

Our Abpromise guarantee covers the use of ab45573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-NIR1 antibody (ab21197)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • CORD5
    • Membrane associated phosphatidylinositol transfer protein 3
    • membrane-associated 3
    • Membrane-associated phosphatidylinositol transfer protein 3
    • MGC157740
    • MGC157741
    • NIR 1
    • NIR-1
    • NIR1
    • Phosphatidylinositol transfer protein
    • Phosphatidylinositol transfer protein, membrane-associated 3
    • PITM3_HUMAN
    • PITPNM
    • PITPnm 3
    • PITPNM family member 3
    • Pitpnm3
    • PYK2 N terminal domain interacting receptor 1
    • Pyk2 N-terminal domain-interacting receptor 1
    • RDGBA3
    • Retinal degeneration B alpha 3
    see all
  • 機能Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.
  • 組織特異性Detected in brain and spleen, and at low levels in ovary.
  • 関連疾患Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) [MIM:600977]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
  • 配列類似性Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
    Contains 1 DDHD domain.
  • 細胞内局在Endomembrane system.
  • Information by UniProt

Human NIR1 peptide (ab45573) 使用論文

ab45573 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"