The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-NIR1 antibody (ab21197)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Membrane associated phosphatidylinositol transfer protein 3
Membrane-associated phosphatidylinositol transfer protein 3
Phosphatidylinositol transfer protein
Phosphatidylinositol transfer protein, membrane-associated 3
PITPNM family member 3
PYK2 N terminal domain interacting receptor 1
Pyk2 N-terminal domain-interacting receptor 1
Retinal degeneration B alpha 3
Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.
Detected in brain and spleen, and at low levels in ovary.
Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) [MIM:600977]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily. Contains 1 DDHD domain.