製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      ASSAREHLLFVRR-C
    • 領域
      2 to 14

特性

Our Abpromise guarantee covers the use of ab23243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • C2 and WW domain-containing protein 2
    • E3 ubiquitin protein ligase HECW2
    • E3 ubiquitin-protein ligase HECW2
    • HECT
    • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
    • Hecw2
    • HECW2_HUMAN
    • KIAA130
    • KIAA1301
    • NEDD4 like E3 ubiquitin protein ligase 2
    • NEDD4 Related E3 Ubiquitin Ligase
    • NEDD4-like E3 ubiquitin-protein ligase 2
    see all
  • 機能
    E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
  • 組織特異性
    Predominantly expressed in adult brain, lung and heart.
  • パスウェイ
    Protein modification; protein ubiquitination.
  • 配列類似性
    Contains 1 C2 domain.
    Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
    Contains 2 WW domains.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab23243 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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