Nerve growth factor receptor (TNFRSF16) associated protein 1
Nerve growth factor receptor associated protein 1
Nerve growth factor receptor-associated protein 1
NGFR-associated protein 1
Ovarian granulosa cell 13.0 kDa protein HGR74
Ovarian granulosa cell protein
ovarian granulosa cell protein (13kD)
p75NTR associated cell death executor
p75NTR-associated cell death executor
機能May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
組織特異性Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
配列類似性Belongs to the BEX family.
ドメインThe nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.
翻訳後修飾Ubiquitinated. Degraded by the proteasome.
細胞内局在Nucleus. Cytoplasm. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.