Human N WASP (phospho Y256) peptide (ab42793)

製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human

関連製品

特性

Our Abpromise guarantee covers the use of ab42793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Human WASP sequence has a two amino acid difference in the region surrounding Tyrosine 291.
  • アプリケーション

    Blocking - Blocking peptide for Anti-N WASP (phospho Y256) antibody (ab23395)

    ELISA

  • 製品の状態Liquid
  • 備考


    Phosphorylation at serine and tyrosine residues regulates the activity of both proteins. WASP is tyrosine phosphorylated at tyrosine 291 after antigen receptor activation in B-cells and collagen stimulation of platelets. Phosphorylation of the analogous site in N WASP (Tyr-256) stimulates its activity, reduces nuclear N WASP, and is required for neurite extension.

    Human WASP sequence has a two amino acid difference in the region surrounding Tyrosine 291.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: PBS

関連情報

  • 別名
    • DKFZp779G0847
    • MGC48327
    • N-WASP
    • Neural Wiskott Aldrich syndrome protein
    • Neural Wiskott-Aldrich syndrome protein
    • NWASP
    • Wasl
    • WASL_HUMAN
    • WASPB
    • Wiskott Aldrich syndrome gene like
    • Wiskott Aldrich syndrome gene like protein
    • Wiskott Aldrich syndrome like
    • WiskottAldrich syndrome like
    see all
  • 機能Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.
  • 配列類似性Contains 1 CRIB domain.
    Contains 1 WH1 domain.
    Contains 2 WH2 domains.
  • 細胞内局在Cytoplasm > cytoskeleton. Nucleus. Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated.
  • Information by UniProt

Human N WASP (phospho Y256) peptide (ab42793) 使用論文

ab42793 has not yet been referenced specifically in any publications.

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