製品の概要

  • 製品名
    Human Myosin 18B peptide

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-DDVASIMKKYLQK
    • 領域
      2555 to 2567

特性

Our Abpromise guarantee covers the use of ab45499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • BK125H2.1
    • DKFZp434C2422
    • DKFZp779C1668
    • MY18B_HUMAN
    • MYO18B
    • myosin 18B
    • myosin XVIIIB
    • Myosin-XVIIIb
    see all
  • 機能
    May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
  • 組織特異性
    Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
  • 配列類似性
    Contains 1 IQ domain.
    Contains 1 myosin head-like domain.
  • 発生段階
    Reaches an expression peak in the third day after induction and remains at similar level during successive myotubule maturation.
  • 細胞内局在
    Cytoplasm. Nucleus. Cytoplasm > myofibril > sarcomere. Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
  • Information by UniProt

参考文献

ab45499 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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