製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab47516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 製品の状態Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • anscription factor 6-like 1
    • Mitochondrial transcription factor 1
    • mitochondrial transcription factor A
    • MtTF1
    • mtTFA
    • TCF 6
    • TCF-6
    • TCF6
    • TCF6L1
    • TCF6L2
    • TCF6L3
    • TFAM
    • TFAM_HUMAN
    • Transcription factor 6
    • Transcription factor 6 like 2
    • Transcription factor 6 like 2 (mitochondrial transcription factor)
    • Transcription factor 6-like 2
    • transcription factor 6-like 3
    • Transcription factor A, mitochondrial
    • Transcription factor A, mitochondrial precursor
    see all
  • 機能Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.
  • 配列類似性Contains 2 HMG box DNA-binding domains.
  • 細胞内局在Mitochondrion.
  • Information by UniProt

Human mtTFA peptide (ab47516) 使用論文

ab47516 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"