製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列SSRKQGSQPRGQQS-C
    • 領域2 to 15

関連製品

特性

Our Abpromise guarantee covers the use of ab23259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Mortality Factor 4 like 2 antibody (ab15700)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • CG6363
    • Eaf3
    • Esa1p associated factor 3 homolog
    • FWP006
    • HsT17725
    • MEAF3
    • MO4L1_HUMAN
    • MORF related gene on chromosome 15
    • MORF-related gene 15 protein
    • Morf4l1
    • MORFRG15
    • Mortality factor 4 like 1
    • Mortality factor 4 like protein 1
    • Mortality factor 4-like protein 1
    • MRG15
    • Protein MSL3-1
    • S863-6
    • Transcription factor-like protein MRG15
    see all
  • 機能Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
  • 配列類似性Belongs to the MRG family.
  • 細胞内局在Nucleus.
  • Information by UniProt

Human MRG15 peptide (ab23259) 使用論文

ab23259 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"