Human Mannan Binding Lectin peptide (237-248) (Carboxyterminal end) (ab45655)

製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      STSHLAVCEFPI
    • 領域
      237 to 248

関連製品

特性

Our Abpromise guarantee covers the use of ab45655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Mannan Binding Lectin antibody (ab31296)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

関連情報

  • 別名
    • COLEC 1
    • COLEC1
    • Collectin-1
    • HSMBPC
    • Lectin, mannose-binding, soluble, 2
    • Mannan binding lectin
    • Mannan binding protein
    • Mannan-binding protein
    • Mannose binding lectin
    • Mannose binding lectin (protein C) 2 soluble
    • Mannose binding lectin (protein C) 2, soluble
    • Mannose binding lectin (protein C) 2, soluble (opsonic defect)
    • Mannose binding lectin 2 soluble
    • Mannose binding lectin 2, soluble (opsonic defect)
    • Mannose binding lectin protein C2 soluble opsonic defect
    • Mannose binding protein
    • Mannose binding protein C
    • Mannose binding protein C precursor
    • Mannose binding protein, serum
    • Mannose-binding lectin
    • Mannose-binding protein C
    • MBL
    • MBL 2
    • MBL2
    • MBL2_HUMAN
    • MBL2D
    • MBP
    • MBP 1
    • MBP C
    • MBP-C
    • MBP1
    • MBPB
    • MBPC
    • MBPD
    • MGC116832
    • MGC116833
    • Opsonic defect
    • protein C
    • Soluble mannose binding lectin
    see all
  • 機能
    Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
  • 組織特異性
    Plasma protein produced mainly in the liver.
  • 関連疾患
    Note=There is an association between low levels of MBL2 and a defect of opsonization which results in susceptibility to frequent and chronic infections.
  • 配列類似性
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab45655 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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