製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab87128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 精製度70 - 90% by HPLC.

  • 製品の状態Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • 9430031G15Rik
    • 9830146M04
    • Latent transforming growth factor beta binding protein 1
    • Latent-transforming growth factor beta-binding protein 1
    • Latent-transforming growth factor beta-binding protein, isoform 1L
    • Latent-transforming growth factor beta-binding protein, isoform 1S
    • LBT1S
    • LTBP-1
    • Ltbp1
    • LTBP1_HUMAN
    • MGC163161
    • TGF-beta1-BP-1
    • Tgfb
    • Transforming growth factor beta-1-binding protein 1
    • Transforming growth factor beta-1-masking protein large subunit
    see all
  • 機能May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
  • 組織特異性Isoform Long is found in fibroblasts.
  • 配列類似性Belongs to the LTBP family.
    Contains 18 EGF-like domains.
    Contains 4 TB (TGF-beta binding) domains.
  • ドメインAssociates covalently with small latent TGF-beta complex via domain TB 3.
  • 翻訳後修飾Contains hydroxylated asparagine residues.
    Isoform Short N-terminus is blocked.
    The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • 細胞内局在Secreted.
  • Information by UniProt

Human LTBP1 peptide (ab87128) 使用論文

ab87128 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"