製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列WEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGG
    • 領域648 to 697

関連製品

特性

Our Abpromise guarantee covers the use of ab111652 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-KHSRP antibody (ab83291)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • Far upstream element-binding protein 2
    • FBP2
    • FUBP2
    • FUBP2_HUMAN
    • FUSE binding protein 2
    • FUSE-binding protein 2
    • KH type splicing regulatory protein
    • KH type splicing regulatory protein (FUSE binding protein 2)
    • KH type-splicing regulatory protein
    • KHSRP
    • KSRP
    • p75
    see all
  • 機能Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
  • 組織特異性Detected in neural and non-neural cell lines.
  • 配列類似性Belongs to the KHSRP family.
    Contains 4 KH domains.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus. Cytoplasm. A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites.
  • Information by UniProt

Human KHSRP peptide (ab111652) 使用論文

ab111652 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111652.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"