Anti-Human Ig light chain 抗体 [MHK-49] (ab48536)


  • 製品名Anti-Human Ig light chain antibody [MHK-49]
    Human Ig light chain 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MHK-49] to Human Ig light chain
  • 特異性This antibody is specific for both soluble and membrane human immunoglobulin light chain kappa. It does not react with human immunoglobulin light chain lambda or heavy chain mu.
  • アプリケーション適用あり: ICC/IF, ELISA, Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein corresponding to Human Human Ig light chain.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名MHK-49
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野


Our Abpromise guarantee covers the use of ab48536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration. This antibody can be used as primary or secondary reagent for immunofluorescent staining or ELISA analysis.
Flow Cyt Use 0.5µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 関連性There are only two types of light chain: kappa and lambda in mammals. Other types of light chains are found in lower vertebrates as the Ig-Light-Iota chain in Chondrichthyes and Teleostei. In each antibody, only one type is present and the two chains are identical. Each light chain has two successive domains: one constant and one variable domain. In humans 60% of light chains are kappa and 40% lambda,whereas in the mouse 95% of light chains are kappa. The amino acid sequences of lambda chains vary slightly at a few positions, allowing them to be classified into subtypes. The number of subtypes varies between species. Monoclonal immunoglobulin free light chains (FLC) are found in the serum and urine (Bence-Jones protein) of patients with a number of B-cell proliferative disorders, including multiple myeloma. Changes in serum FLC concentrations can provide a rapid and sensitive indication of response to treatment.
  • 細胞内局在Cell Membrane: single-pass type I membrane protein and Secreted
  • 参照データベース
  • 別名
    • HCAK1 antibody
    • Ig kappa chain antibody
    • IGKC antibody
    • Immunoglobulin kappa constant antibody
    • immunoglobulin kappa light chain (VJ) antibody
    • kappa 1 immunoglobulin light chain antibody
    • KM antibody
    • MGC111575 antibody
    • MGC62011 antibody
    • MGC72072 antibody
    • MGC88770 antibody
    • MGC88771 antibody
    • MGC88809 antibody
    see all

Anti-Human Ig light chain antibody [MHK-49] (ab48536) 使用論文

ab48536 has not yet been referenced specifically in any publications.

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