製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-DRHKETLKSKTQ
    • 領域
      362 to 373

関連製品

特性

Our Abpromise guarantee covers the use of ab48064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-HSD3B1 antibody (ab48018)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • 3 beta and steroid delta isomerase 1
    • 3 beta and steroid hydroxy delta 5 steroid dehydrogenase
    • 3 beta HSD I
    • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I
    • 3-beta-HSD I
    • 3-beta-hydroxy-5-ene steroid dehydrogenase
    • 3BETAHSD
    • 3BH
    • 3BHS1_HUMAN
    • 3BHSD
    • Delta-5-3-ketosteroid isomerase
    • HGNC:5217
    • HSD3B
    • HSD3B1
    • HSDB3
    • HSDB3A
    • Hydroxy delta 5 steroid dehydrogenase
    • Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1
    • Progesterone reductase
    • SDR11E1
    • Steroid Delta-isomerase
    • trophoblast antigen
    • Trophoblast antigen FDO161G
    see all
  • 機能
    3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
  • 組織特異性
    Placenta and skin. Predominantly expressed in mammary gland tissue.
  • パスウェイ
    Lipid metabolism; steroid biosynthesis.
  • 配列類似性
    Belongs to the 3-beta-HSD family.
  • 細胞内局在
    Endoplasmic reticulum membrane. Mitochondrion membrane.
  • Information by UniProt

参考文献

ab48064 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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