製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-HFGLFPANYVKLLE
    • 領域
      473 to 486

特性

Our Abpromise guarantee covers the use of ab22787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Cortactin like
    • CTTNL
    • HCLS 1
    • Hcls1
    • HCLS1_HUMAN
    • Hematopoietic cell specific Lyn substrate 1
    • Hematopoietic cell-specific LYN substrate 1
    • Hematopoietic lineage cell-specific protein
    • HS 1
    • HS1
    • LckBP1
    • OTTHUMP00000215180
    • OTTHUMP00000215182
    • p75
    see all
  • 機能
    Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • 組織特異性
    Expressed only in tissues and cells of hematopoietic origin.
  • 配列類似性
    Contains 4 cortactin repeats.
    Contains 1 SH3 domain.
  • 発生段階
    Expressed in early stage of myeloid and erythroid differentiation.
  • 翻訳後修飾
    Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.
  • 細胞内局在
    Membrane. Cytoplasm. Mitochondrion.
  • Information by UniProt

参考文献

ab22787 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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