製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-RDAYREAQQLVQR
    • 領域648 to 660

関連製品

特性

Our Abpromise guarantee covers the use of ab48046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-GRK2 antibody (ab47999)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • ADRBK1
    • Adrenergic beta receptor kinase 1
    • ARBK1_HUMAN
    • BARK
    • BARK1
    • Beta adrenergic receptor kinase 1
    • Beta ARK 1
    • Beta ARK1
    • Beta-adrenergic receptor kinase 1
    • Beta-ARK-1
    • FLJ16718
    • G protein coupled receptor kinase 2
    • G-protein coupled receptor kinase 2
    • GRK2
    see all
  • 機能Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
  • 組織特異性Expressed in peripheral blood leukocytes.
  • 配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 PH domain.
    Contains 1 protein kinase domain.
    Contains 1 RGS domain.
  • Information by UniProt

Human GRK2 peptide (ab48046) 使用論文

ab48046 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab48046.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"