Human Glucose Transporter GLUT2 peptide (ab105630)

製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human

関連製品

特性

Our Abpromise guarantee covers the use of ab105630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Glucose Transporter GLUT2 antibody (ab95256)

  • 精製度
    70 - 90% by HPLC.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • Glucose Transporter 2
    • Glucose Transporter GLUT2
    • Glucose transporter type 2
    • Glucose transporter type 2 liver
    • Glucose transporter, liver/islet
    • GLUT-2
    • GLUT2
    • GTR2_HUMAN
    • GTT2
    • liver
    • SLC2A2
    • Solute carrier family 2 (facilitated glucose transporter) member 2
    • Solute carrier family 2 facilitated glucose transporter member 2
    • Solute carrier family 2, facilitated glucose transporter member 2
    see all
  • 機能
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • 組織特異性
    Liver, insulin-producing beta cell, small intestine and kidney.
  • 関連疾患
    Fanconi-Bickel syndrome
  • 配列類似性
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • 翻訳後修飾
    N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • 細胞内局在
    Membrane.
  • Information by UniProt

Human Glucose Transporter GLUT2 peptide (ab105630) 使用論文

ab105630 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application
Western blot
We have used whole kidney lysate form normoglycemic mice or STZ induced diabetic mice after 16 weeks from injection.

Application: Western blot
Sample: whole Kidney lysate
Gel Running Conditions: Reduced Denaturing
Loading amount: 30 µg

Treatment: Five consecutive intraperitoneal Strreptozotocin injections (Cayman Chemical 50 mg/kg per day), Samples from kidneys after 16 weeks from last injection.
Specification: Mouse Kidney
Blocking step: Milk as blocking agent for 1 hour, Temperature: 25°C

First antibody (ab95256) with/ without Blocking peptide (ab105630), ratio 1:10-
Incubation time 16 hour(s) , Temperature: 4°C
Dilution 1/1000

Secondary antibody
Dilution 1/10000
Name ab97085
Host species: Rabbit
Clonality: Polyclonal
Conjugation: Horse Radish Peroxidase
Detection
Detection method ECL+
Exposure 2 minute(s) and 0 second(s)


lanes 1-3, 7-9 are from WT normoglycemic mice
lanes 4-6, 10-12 are from STZ induced diabetic mice

lanes 1-6 with ab95256
lanes 7-12 with ab95256+ ab105630

STZ- Streptozotocine
bp- Blocking peptide
Username

Shiran Udi

Verified customer

投稿 Jul 03 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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