Human Glucose Transporter GLUT2 peptide (ab105630)

製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human

関連製品

特性

Our Abpromise guarantee covers the use of ab105630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Glucose Transporter GLUT2 antibody (ab95256)

  • 精製度
    70 - 90% by HPLC.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • Glucose Transporter 2
    • Glucose Transporter GLUT2
    • Glucose transporter type 2
    • Glucose transporter type 2 liver
    • Glucose transporter, liver/islet
    • GLUT-2
    • GLUT2
    • GTR2_HUMAN
    • GTT2
    • liver
    • SLC2A2
    • Solute carrier family 2 (facilitated glucose transporter) member 2
    • Solute carrier family 2 facilitated glucose transporter member 2
    • Solute carrier family 2, facilitated glucose transporter member 2
    see all
  • 機能
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • 組織特異性
    Liver, insulin-producing beta cell, small intestine and kidney.
  • 関連疾患
    Fanconi-Bickel syndrome
  • 配列類似性
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • 翻訳後修飾
    N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • 細胞内局在
    Membrane.
  • Information by UniProt

参考文献

ab105630 has not yet been referenced specifically in any publications.

レビューと Q&A

Abreviews
Application
Western blot
We have used whole kidney lysate form normoglycemic mice or STZ induced diabetic mice after 16 weeks from injection.

Application: Western blot
Sample: whole Kidney lysate
Gel Running Conditions: Reduced Denaturing
Loading amount: 30 µg

Treatment: Five consecutive intraperitoneal Strreptozotocin injections (Cayman Chemical 50 mg/kg per day), Samples from kidneys after 16 weeks from last injection.
Specification: Mouse Kidney
Blocking step: Milk as blocking agent for 1 hour, Temperature: 25°C

First antibody (ab95256) with/ without Blocking peptide (ab105630), ratio 1:10-
Incubation time 16 hour(s) , Temperature: 4°C
Dilution 1/1000

Secondary antibody
Dilution 1/10000
Name ab97085
Host species: Rabbit
Clonality: Polyclonal
Conjugation: Horse Radish Peroxidase
Detection
Detection method ECL+
Exposure 2 minute(s) and 0 second(s)


lanes 1-3, 7-9 are from WT normoglycemic mice
lanes 4-6, 10-12 are from STZ induced diabetic mice

lanes 1-6 with ab95256
lanes 7-12 with ab95256+ ab105630

STZ- Streptozotocine
bp- Blocking peptide
Username

Shiran Udi

Verified customer

投稿 Jul 03 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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