製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列SCGHPEVGRLGGGPALYPPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGL
    • 領域1009 to 1058

関連製品

特性

Our Abpromise guarantee covers the use of ab86150 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Gli1 antibody (ab49314)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • GLI
    • Gli 1
    • GLI family zinc finger 1
    • GLI Kruppel family member 1
    • gli1
    • GLI1_HUMAN
    • Glioma associated oncogene 1
    • Glioma associated oncogene homolog
    • Glioma associated oncogene homolog 1 (zinc finger protein)
    • Glioma-associated oncogene
    • Oncogene GLI
    • Zfp 5
    • Zfp5
    • Zinc finger protein GLI 1
    • Zinc finger protein GLI1
    see all
  • 機能Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
  • 組織特異性Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract.
  • 配列類似性Belongs to the GLI C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.
  • 翻訳後修飾Phosphorylated in vitro by ULK3.
  • 細胞内局在Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.
  • Information by UniProt

Human Gli1 peptide (ab86150) 使用論文

ab86150 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"