製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列Pyr-GPWLEEEEEAGWMDF
    • 領域77 to 92

関連製品

特性

Our Abpromise guarantee covers the use of ab42257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Gastrin antibody (ab14182)

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

  • 再構成Resuspend in 60% acetonitrile in 0.01M ammoiumbicarbonate for required concentration (vial content is 0.1 mg).

関連情報

  • 別名
    • Component II
    • G14
    • G17
    • G34
    • G52
    • G6
    • GAS
    • Gast
    • GAST_HUMAN
    • Gastrin
    • Gastrin component I
    • Gastrin component II
    • Gastrin component III
    • Gastrin precursor
    • Gastrin-14
    • Gastrin-17
    • Gastrin-34
    • Gastrin-52
    • Gastrin-6
    • Gastrin-71
    see all
  • 機能Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
  • 配列類似性Belongs to the gastrin/cholecystokinin family.
  • 翻訳後修飾Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
    Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
  • 細胞内局在Secreted.
  • Information by UniProt

Human Gastrin peptide (ab42257) 使用論文

ab42257 has not yet been referenced specifically in any publications.

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