製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-GLRPPYPTADHMLA
    • 領域730 to 743

関連製品

特性

Our Abpromise guarantee covers the use of ab23208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-gamma Catenin antibody (ab11799)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • ARVD 12
    • ARVD12
    • Catenin (cadherin associated protein), gamma 80kDa
    • catenin (cadherin-associated protein) gamma (80kD)
    • Catenin gamma
    • CTNNG
    • Desmoplakin 3
    • Desmoplakin III
    • Desmoplakin-3
    • Desmoplakin3
    • DesmoplakinIII
    • DP 3
    • DP III
    • DP3
    • DPIII
    • gamma catenin
    • Junction plakoglobin
    • JUP
    • OTTHUMP00000164732
    • OTTHUMP00000164735
    • OTTHUMP00000164738
    • PDGB
    • PKGB
    • PLAK_HUMAN
    • PLAKOGLOBIN
    see all
  • 機能Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
  • 関連疾患Defects in JUP are the cause of Naxos disease (NXD) [MIM:601214]. NXD is an autosomal recessive disorder combining diffuse non-epidermolytic palmoplantar keratoderma with arrhythmogenic right ventricular dysplasia/cardiomyopathy and woolly hair.
    Defects in JUP are the cause of familial arrhythmogenic right ventricular dysplasia type 12 (ARVD12) [MIM:611528]; also called arrhythmogenic right ventricular cardiomyopathy 12 (ARVC12). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • 配列類似性Belongs to the beta-catenin family.
    Contains 9 ARM repeats.
  • 細胞内局在Cell junction > adherens junction. Cell junction > desmosome. Cytoplasm > cytoskeleton. Membrane. Cytoplasmic in a soluble and membrane-associated form.
  • Information by UniProt

Human gamma Catenin peptide (ab23208) 使用論文

ab23208 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"