製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-AAALDLSGRRG
    • 領域664 to 674

関連製品

特性

Our Abpromise guarantee covers the use of ab23166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-GADD34 antibody (ab9869)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Apoptosis associated protein
    • GADD 34
    • Growth arrest and DNA damage inducible 34
    • Growth arrest and DNA damage-inducible protein GADD34
    • Myeloid differentiation primary response protein MyD116 homolog
    • Ppp1r15a
    • PR15A_HUMAN
    • Protein phosphatase 1 regulatory (inhibitor) subunit 15A
    • Protein phosphatase 1 regulatory subunit 15A
    see all
  • 機能Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
  • 配列類似性Belongs to the PPP1R15 family.
  • 翻訳後修飾Phosphorylated on tyrosine by LYN; which impairs its antiproliferative activity.
  • 細胞内局在Endoplasmic reticulum.
  • Information by UniProt

Human GADD34 peptide (ab23166) 使用論文

ab23166 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23166.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"