製品の概要

  • 製品名
    Human FOXH1 peptide

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      GPCSGSRLGPPEAE
    • 領域
      2 to 15

特性

Our Abpromise guarantee covers the use of ab23092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • FAST 1
    • Fast 2
    • Fast-1
    • Fast-2
    • FAST1
    • Fast2
    • Forkhead activin signal transducer 1
    • Forkhead activin signal transducer 2
    • Forkhead box H1
    • Forkhead box protein H1
    • FOX H1
    • FOXH 1
    • FOXH1
    • FOXH1_HUMAN
    • hFAST 1
    • hFAST-1
    • hFAST1
    • Human homolog of Xenopus forkhead activin signal transducer 1
    • TGF beta/Activin signal transducer FAST1
    see all
  • 機能
    Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Contains 1 fork-head DNA-binding domain.
  • ドメイン
    The FM region is required for binding SMAD2/SMAD4 complexes. FM2 is more effective than FM1 and only interacts with phosphorylated SMAD2 that is in an activated SMAD complex.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

参考文献

ab23092 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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