製品の概要

  • 製品名
    Human FGD1 peptide

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-TAEPPESPQTRDKT
    • 領域
      948 to 961

特性

Our Abpromise guarantee covers the use of ab45555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • AAS
    • Faciogenital dysplasia 1 protein
    • FGD1
    • FGD1_HUMAN
    • FGDY
    • FYVE RhoGEF and PH domain containing protein 1
    • FYVE, RhoGEF and PH domain-containing protein 1
    • Rho/Rac GEF
    • Rho/Rac guanine nucleotide exchange factor FGD1
    • ZFYVE3
    • Zinc finger FYVE domain containing protein 3
    • Zinc finger FYVE domain-containing protein 3
    see all
  • 機能
    Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
  • 組織特異性
    Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
  • 関連疾患
    Aarskog-Scott syndrome
    Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation.
  • 配列類似性
    Contains 1 DH (DBL-homology) domain.
    Contains 1 FYVE-type zinc finger.
    Contains 2 PH domains.
  • ドメイン
    The DH domain is involved in interaction with CCPG1.
  • 細胞内局在
    Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Associated with membrane ruffles and lamellipodia.
  • Information by UniProt

参考文献

ab45555 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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