製品の概要

  • 製品名Human FGD1 peptide

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-TAEPPESPQTRDKT
    • 領域948 to 961

特性

Our Abpromise guarantee covers the use of ab45555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • AAS
    • Faciogenital dysplasia 1 protein
    • FGD1
    • FGD1_HUMAN
    • FGDY
    • FYVE RhoGEF and PH domain containing protein 1
    • FYVE, RhoGEF and PH domain-containing protein 1
    • Rho/Rac GEF
    • Rho/Rac guanine nucleotide exchange factor FGD1
    • ZFYVE3
    • Zinc finger FYVE domain containing protein 3
    • Zinc finger FYVE domain-containing protein 3
    see all
  • 機能Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
  • 組織特異性Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
  • 関連疾患Aarskog-Scott syndrome
    Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation.
  • 配列類似性Contains 1 DH (DBL-homology) domain.
    Contains 1 FYVE-type zinc finger.
    Contains 2 PH domains.
  • ドメインThe DH domain is involved in interaction with CCPG1.
  • 細胞内局在Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Associated with membrane ruffles and lamellipodia.
  • Information by UniProt

Human FGD1 peptide (ab45555) 使用論文

ab45555 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45555.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"