Human Estrogen Related Receptor alpha peptide (ab39777)

製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列MSSQVVGIEPLYIKAE
    • 領域1 to 16

特性

Our Abpromise guarantee covers the use of ab39777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Neutralising

    Blocking - Blocking peptide for Anti-Estrogen Related Receptor alpha antibody - ChIP Grade (ab16363)

  • 精製度> 90 % SDS-PAGE.
    This peptide is greater than 70% pure.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Double distilled water or equivalent after reconstitution.

関連情報

  • 別名
    • Err 1
    • ERR a
    • ERR alpha
    • ERR-alpha
    • Err1
    • ERR1 protein
    • ERR1_HUMAN
    • ERRa
    • ERRalpha
    • ESRL 1
    • ESRL1
    • ESRR A
    • Esrra
    • Estrogen receptor like 1
    • Estrogen receptor related 1
    • estrogen receptor related receptor alpha
    • Estrogen receptor-like 1
    • Estrogen related receptor alpha
    • Estrogen-related receptor alpha
    • Estrra
    • hERR1
    • NR3B1
    • Nuclear receptor subfamily 3 group B member 1
    • Steroid hormone receptor ERR1
    see all
  • 機能Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
  • 配列類似性Belongs to the nuclear hormone receptor family. NR3 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 翻訳後修飾Phosphorylation on Ser-19 enhances sumoylation on Lys-14 increasing repression of transcriptional activity.
    Sumoylated by SUMO2. Main site is Lys-14 which is enhanced by phosphorylation on Ser-19, cofactor activation, and by interaction with PIAS4. Sumoylation enhances repression of transcriptional activiy, but has no effect on subcellular location nor on DNA binding.
  • 細胞内局在Nucleus.
  • Information by UniProt

Human Estrogen Related Receptor alpha peptide (ab39777) 使用論文

ab39777 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab39777.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"