製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列PNTRLPTSHMPSH

関連製品

特性

Our Abpromise guarantee covers the use of ab87722 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-ERG antibody (ab77258)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • Avian erythroblastosis virus E-26 (v-ets) oncogene related
    • D030036I24Rik
    • Erg
    • Erg 3
    • ERG/EWS fusion gene, included
    • ERG/FUS fusion gene, included
    • ERG/TMPSSR2 fusion gene, included
    • ERG_HUMAN
    • ERG1, included
    • ERG2, included
    • ets related
    • ETS-related gene
    • KCNH2
    • Oncogene ERG
    • p55
    • TMPRSS2/ERG fusion
    • Transcriptional regulator ERG
    • transcriptional regulator ERG (transforming protein ERG)
    • Transforming protein ERG
    • v ets avian erythroblastosis virus E26 oncogene
    • v ets avian erythroblastosis virus E26 oncogene related
    • v ets erythroblastosis virus E26 oncogene homolog
    • v ets erythroblastosis virus E26 oncogene like
    • v ets erythroblastosis virus E26 oncogene like isoform 2
    • v-ets erythroblastosis virus E26 oncogene
    • v-ets erythroblastosis virus E26 oncogene homolog (avian)
    • V-ets erythroblastosis virus E26 oncogene like (Avian), isoform CRA_e
    see all
  • 機能Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
  • 関連疾患Defects in ERG are a cause of Ewing sarcoma (ES) [MIM:612219]. A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=A chromosomal aberration involving ERG is found in patients with Erwing sarcoma. Translocation t(21;22)(q22;q12) with EWSR1.
    Note=Chromosomal aberrations involving ERG have been found in acute myeloid leukemia (AML). Translocation t(16;21)(p11;q22) with FUS. Translocation t(X;21)(q25-26;q22) with ELF4.
  • 配列類似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
    Contains 1 PNT (pointed) domain.
  • 細胞内局在Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt

Human ERG peptide (ab87722) 使用論文

ab87722 has not yet been referenced specifically in any publications.

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