製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-PKEPSSYDFVYHYG
    • 領域
      707 to 720

関連製品

特性

Our Abpromise guarantee covers the use of ab22879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-ELMO2 antibody (ab2240)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • CED 12
    • Ced 12 homolog 2
    • CED 12 homolog A
    • CED 12A
    • CED-12
    • ced-12 homolog 2
    • CED12
    • CED12 homolog A
    • CED12, C. elegans, homolog of, 2
    • CED12A
    • ELMO 2
    • ELMO-2
    • ELMO2
    • ELMO2_HUMAN
    • Engulfment and cell motility 2
    • Engulfment and cell motility 2 (ced 12 homolog, C. elegans)
    • Engulfment and cell motility gene 2
    • Engulfment and cell motility protein 2
    • FLJ11656
    • hCED 12A
    • hCED-12A
    • hCED12A
    • KIAA1834
    • OTTHUMP00000031762
    • PH domain protein CED12A
    • Protein ced 12 homolog A
    • Protein ced-12 homolog A
    see all
  • 機能
    Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 組織特異性
    Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
  • 配列類似性
    Contains 1 ELMO domain.
    Contains 1 PH domain.
  • 細胞内局在
    Cytoplasm. Cytoplasm > cytosol. Membrane.
  • Information by UniProt

参考文献

ab22879 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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