製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列PKEPSNYDFVYDCN
    • 領域714 to 727

関連製品

特性

Our Abpromise guarantee covers the use of ab22878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-ELMO1 antibody (ab2239)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • CED 12
    • Ced 12 homolog
    • Ced 12 homolog 1
    • CED-12
    • CED12
    • Ced12 homolog
    • Ced12 homolog 1
    • ELMO 1
    • ELMO-1
    • Elmo1
    • ELMO1_HUMAN
    • Engulfment and cell motility 1
    • Engulfment and cell motility protein 1
    • KIAA0281
    • MGC126406
    • Protein ced-12 homolog
    see all
  • 機能Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 組織特異性Widely expressed, with a higher expression in the spleen and placenta.
  • 配列類似性Contains 1 ELMO domain.
    Contains 1 PH domain.
  • 翻訳後修飾Phosphorylated by HCK.
  • 細胞内局在Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
  • Information by UniProt

Human ELMO1 peptide (ab22878) 使用論文

ab22878 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"