製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      SHPQKDDGDNPETI
    • 領域
      359 to 372

関連製品

特性

Our Abpromise guarantee covers the use of ab39763 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Neutralising

    Blocking - Blocking peptide for Anti-EDG1 antibody (ab11424)

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • CD363
    • CHEDG 1
    • CHEDG1
    • D1S3362
    • ECGF 1
    • ECGF1
    • EDG 1
    • EDG1
    • endothelial differentiation G protein coupled receptor 1
    • Endothelial differentiation G-protein coupled receptor 1
    • Endothelial differentiation sphingolipid G protein coupled receptor 1
    • FLJ58121
    • G protein coupled sphingolipid receptor
    • g protein-coupled receptor edg-1
    • S1P receptor 1
    • S1P receptor Edg 1
    • S1P receptor Edg-1
    • S1P receptor Edg1
    • S1P(1) receptor
    • S1P1
    • s1pr1
    • S1PR1_HUMAN
    • sphingolipid g-protein-coupled receptor 1
    • Sphingosine 1 phosphate receptor Edg 1
    • Sphingosine 1 phosphate receptor EDG1
    • sphingosine 1- phosphate receptor 1
    • Sphingosine 1-phosphate receptor 1
    • Sphingosine 1-phosphate receptor Edg-1
    • Sphingosine 1phosphate receptor type 1 S1P1
    see all
  • 機能
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.
  • 組織特異性
    Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾
    S1P-induced endothelial cell migration requires the PKB/AKT1-mediated phosphorylation of the third intracellular loop at the Thr-236 residue.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt

参考文献

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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