製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-DNEDSDTKKSYVN
    • 領域
      493 to 505

特性

Our Abpromise guarantee covers the use of ab48052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • EAA3_HUMAN
    • EAAC 1
    • EAAC1
    • EAAT 3
    • Excitatory amino acid carrier 1
    • Excitatory amino acid carrier1
    • Excitatory amino acid transporter 3
    • Excitatory amino acid transporter3
    • Excitatory amino-acid carrier 1
    • GLUTAMATE TRANSPORTER, HIGH-AFFINITY
    • MEAAC 1
    • MEAAC1
    • Neuronal and epithelial glutamate transporter
    • REAAC 1
    • REAAC1
    • Slc1 a1
    • Slc1a 1
    • SLC1A1
    • Sodium dependent glutamate/aspartate transporter 3
    • Sodium-dependent glutamate/aspartate transporter 3
    • Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1
    • SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1
    • Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
    • Solute carrier family 1 member 1
    • Solute carrier family 1, member 1
    see all
  • 機能
    Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5.
  • 組織特異性
    Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).
  • 配列類似性
    Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt

参考文献

ab48052 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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