製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      TRERRKGPAPCDRP
    • 領域
      483 to 490

関連製品

特性

Our Abpromise guarantee covers the use of ab22816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-DOK3 antibody (ab1357)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Docking protein 3
    • DOK 3
    • DOK Like Protein
    • Dok3
    • DOK3_HUMAN
    • DOKL Pending
    • Downstream of tyrosine kinase 3
    • p62 DOK Like Protein
    see all
  • 機能
    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function.
  • 組織特異性
    Expressed in spleen.
  • 配列類似性
    Belongs to the DOK family. Type A subfamily.
    Contains 1 IRS-type PTB domain.
    Contains 1 PH domain.
  • ドメイン
    PTB domain mediates receptor interaction.
  • 翻訳後修飾
    Constitutively tyrosine-phosphorylated.
    On IL2 stimulation, phosphorylated on C-terminal tyrosine residues possibly by Src kinases. Can also be phosphorylated by ABL kinase.
  • 細胞内局在
    Cytoplasm. Cell membrane.
  • Information by UniProt

Human DOK3 peptide (ab22816) 使用論文

ab22816 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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