製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab16277 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • AA408962
    • AA553318
    • AI844835
    • Cphn 2
    • Cphn2
    • Cyclophilin B
    • Cyclophilin like protein
    • CyP 20b
    • CYP S1
    • CYP-S1
    • CYPB
    • EC 5.2.1.8
    • MGC14109
    • MGC2224
    • OI9
    • peptidyl prolyl cis trans isomerase B
    • Peptidyl prolyl cis trans isomerase B precursor
    • Peptidyl-prolyl cis-trans isomerase B
    • Peptidylprolyl isomerase B
    • peptidylprolyl isomerase B (cyclophilin B)
    • PPIase
    • PPIase B
    • Ppib
    • PPIB_HUMAN
    • Rotamase
    • Rotamase B
    • S cyclophilin
    • S-cyclophilin
    • SCYLP
    see all
  • 機能PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • 関連疾患Defects in PPIB are the cause of osteogenesis imperfecta type 9 (OI9) [MIM:259440]. OI9 is a connective tissue disorder characterized by bone fragility, low bone mass and bowing of limbs due to multiple fractures. Short limb dwarfism and blue sclerae are observed in some but not all patients.
  • 配列類似性Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
    Contains 1 PPIase cyclophilin-type domain.
  • 細胞内局在Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Human Cyclophilin B peptide (ab16277) 使用論文

ab16277 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"