438 to 450
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-CSK antibody (ab744)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- C SRC
- C SRC kinase
- C src Tyrosine Kinase
Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
Expressed in lung and macrophages.
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
Cytoplasm. Cell membrane. Mainly cytoplasmic, also present in lipid rafts.
Information by UniProt
has not yet been referenced specifically in any publications.
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