製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-EKLSRRSHDLHTL
    • 領域728 to 740

関連製品

特性

Our Abpromise guarantee covers the use of ab23280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-CENTB1 antibody (ab15903)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • ACAP 1
    • ACAP1
    • ACAP1_HUMAN
    • Arf GAP with coiled coil ANK repeat and PH domains 1
    • Arf GAP with coiled coil, ankyrin repeat, and pleckstrin homology domains 1
    • Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
    • ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
    • CENT B1
    • Centaurin beta 1
    • Centaurin-beta-1
    • CENTB 1
    • Cnt b1
    • Cnt-b1
    • Cntb1
    • KIAA0050
    see all
  • 機能GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.
  • 組織特異性Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
  • 配列類似性Contains 3 ANK repeats.
    Contains 1 Arf-GAP domain.
    Contains 1 BAR domain.
    Contains 1 PH domain.
  • ドメインPH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes.
  • 翻訳後修飾Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
  • Information by UniProt

Human CENTB1 peptide (ab23280) 使用論文

ab23280 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23280.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"