製品の概要

法規制情報

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列の追加情報Immunizing Peptide (Blocking) for ab24504.

関連製品

特性

Our Abpromise guarantee covers the use of ab52122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-CD44 antibody (ab24504)

  • 精製度> 90 % SDS-PAGE.

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: 0.1% BSA, PBS, pH 7.2

関連情報

  • 別名
    • LHR
    • BA-1
    • CD 44
    • CD44
    • CD44 antigen
    • CD44 molecule
    • CD44 molecule (Indian blood group)
    • CD44_HUMAN
    • CDw44
    • Cell surface glycoprotein CD44
    • chondroitin sulfate proteoglycan 8
    • CSPG8
    • ECMR-III
    • Epican
    • Extracellular matrix receptor III
    • GP90 lymphocyte homing/adhesion receptor
    • HCELL
    • hematopoietic cell E- and L-selectin ligand
    • Heparan sulfate proteoglycan
    • Hermes antigen
    • homing function and Indian blood group system
    • HSA
    • HUTCH-I
    • HUTCH1
    • Hyaluronate receptor
    • IN
    • MC56
    • MDU2
    • MDU3
    • MGC10468
    • MIC4
    • MUTCH1
    • PGP-1
    • PGP-I
    • PGP1
    • Phagocytic glycoprotein 1
    • Phagocytic glycoprotein I
    see all
  • 機能Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
  • 組織特異性Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
  • 配列類似性Contains 1 Link domain.
  • ドメインThe lectin-like LINK domain is responsible for hyaluronan binding.
  • 翻訳後修飾Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors.
    N-glycosylated.
    O-glycosylated; contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s).
    Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672.
  • 細胞内局在Membrane.
  • Information by UniProt

Human CD44 peptide (ab52122) 使用論文

ab52122 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam regarding ab52122.


While the specific sequence is proprietary, I can tell you that the peptide is a short sequence surrounding amino acid 39 of the human protein.


I hope this information is hel...

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Thank you for your enquiry.
CD44 protein has a lectin-like LINK domain (41, 78, 79, 105) which is responsible for hyaluronan binding. However, we have no information if these two product (ab52122 and ab41477) bind to hyaluronic acid, no data avail...

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Thank you for your enquiry. I have contacted the originator of the product but unfortunately, the peptide sequence information is proprietary and can not be released. However, they did confirm that the peptide contains 17 amino acids. Please rest as...

Read More

Thank you for your enquiry. This product contains 18 amino acids (detail sequence is proprietary). The mol. Wt is 2011Da. I am afraid that this is all information we can provide. Please let me know if I can help with anything else.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"