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Tissue: Breast Location: Left breast Diagnosis: Infiltrating ductal carcinoma Stage: IIB T2N1M0 Grade: II Gross findings: Tumor size 4 cm, ill demarcated. Cut section firm and white. Ipsilateral axillary lymph nodes examined: 12. Microscopic findings: The tumor is composed of proliferation of malignant epithelial cells. The epithelial cells are arranged as groups which have invaded the stroma. The tumor cells have irregular, basophilic nuclei and abundant cytoplasm. Nuclear chromatin is coarse with prominent nuclei. Mitotic figures are evident. The stroma is infiltrated by small numbers of chronic inflammatory cells. Necroses are seen but blood vessel invasions are not revealed. The lymph nodes show metastases (2/12).
This product belongs to a range of individual sets of lysates that were extracted from very specific tissues and are gender-, cancer subtype-, tumor grade- and cellular morphology- specific. They allow for consistency, reproducibility, and comparative studies from experiment to experiment, due to the existence of specific (matched) lysates that can be used as controls. Two extractions from each tissue were performed, extraction 1 yielding the soluble protein fraction and extraction 2 the insoluble protein fraction. Please find below a range of products that relate to ab43375: Extraction 1: soluble protein fraction ab43373 Human Breast Tumor Tissue lysate ab43372 Human Breast Normal Tissue lysate (matched) Extraction 2: insoluble protein fraction ab43375 Human Breast Tumor Tissue lysate ab43374 Human Breast Normal Tissue lysate (matched)
ab43375 has not yet been referenced specifically in any publications.