製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-SSMTDTPGNPAAP
    • 領域563 to 575

関連製品

特性

Our Abpromise guarantee covers the use of ab23111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Bag3 antibody (ab5898)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • BAG 3
    • BAG family molecular chaperone regulator 3
    • BAG-3
    • Bag3
    • BAG3_HUMAN
    • Bcl 2 binding protein
    • Bcl-2-associated athanogene 3
    • Bcl-2-binding protein Bis
    • BCL2 associated athanogene 3
    • BCL2 binding athanogene 3
    • BIS
    • CAIR 1
    • Docking protein CAIR 1
    • Docking protein CAIR-1
    • MFM6
    see all
  • 機能Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.
  • 関連疾患Defects in BAG3 are the cause of myopathy myofibrillar BAG3-related (MFM-BAG3) [MIM:612954]. A neuromuscular disorder that results in early-onset, severe, progressive, diffuse muscle weakness associated with cardiomyopathy, severe respiratory insufficiency during adolescence, and a rigid spine in some patients. At ultrastructural level, muscle fibers display structural alterations consisting of replacement of the normal myofibrillar markings by small, dense granules, or larger hyaline masses, or amorphous material.
  • 配列類似性Contains 1 BAG domain.
    Contains 2 WW domains.
  • Information by UniProt

Human Bag3 peptide (ab23111) 使用論文

ab23111 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"