Human Asialoglycoprotein Receptor 1 peptide (ab98248)

製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab98248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 精製度70 - 90% by HPLC.

  • 製品の状態Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • ASGP-R 1
    • ASGPR
    • ASGPR 1
    • ASGPR1
    • Asgr1
    • ASGR1_HUMAN
    • Asialoglycoprotein receptor 1
    • C type lectin domain family 4 member H1
    • C-type lectin domain family 4 member H1
    • CLEC4H1
    • Hepatic lectin H1
    • HL-1
    see all
  • 機能Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
  • 組織特異性Expressed exclusively in hepatic parenchymal cells.
  • 配列類似性Contains 1 C-type lectin domain.
  • 翻訳後修飾Phosphorylated on a cytoplasmic Ser residue.
  • 細胞内局在Membrane.
  • Information by UniProt

Human Asialoglycoprotein Receptor 1 peptide (ab98248) 使用論文

ab98248 has not yet been referenced specifically in any publications.

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