製品の概要

  • 製品名Human APPL peptide

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-DLGEGGKKRESEA
    • 領域697 to 703

特性

Our Abpromise guarantee covers the use of ab23103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Adapter protein containing PH domain
    • Adaptor Protein Containing pH Domain
    • Adaptor protein containing pH domain PTB domain and leucine zipper motif
    • Adaptor protein containing pH domain PTB domain and leucine zipper motif 1
    • AKT2 INTERACTOR
    • APPL 1
    • Appl1
    • DCC interacting protein 13 alpha
    • DCC-interacting protein 13-alpha
    • DIP 13 alpha
    • DIP13 alpha
    • Dip13-alpha
    • DIP13alpha
    • DP13A_HUMAN
    • KIAA1428
    • PTB Domain and Leucine Zipper Motif
    • PTB domain and leucine zipper motif 1
    • Signaling adaptor protein DIP13alpha
    see all
  • 機能Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.
  • 組織特異性High levels in heart, ovary, pancreas and skeletal muscle.
  • 配列類似性Contains 1 PH domain.
    Contains 1 PID domain.
  • ドメインOverexpression of an N-terminal domain (residues 1-319) or a C-terminal region (residues 273-709) has a proapoptotic effect.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Early endosome membrane. Nucleus. Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
  • Information by UniProt

Human APPL peptide (ab23103) 使用論文

ab23103 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23103.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"