製品の概要

  • 製品名
    Human ABCB7 peptide

製品の詳細

  • 由来
    Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab66358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 精製度
    70 - 90% by HPLC.

  • 製品の状態
    Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • ABC transporter 7 protein
    • ABC7
    • Abcb7
    • ABCB7_HUMAN
    • ASAT
    • Atm1p
    • ATP binding cassette 7
    • ATP binding cassette sub family B (MDR/TAP) member 7
    • ATP binding cassette sub family B member 7
    • ATP binding cassette sub family B member 7 mitochondrial
    • ATP binding cassette transporter 7
    • ATP-binding cassette sub-family B member 7
    • ATP-binding cassette transporter 7
    • EST140535
    • MDR7
    • mitochondrial
    • Multidrug resistance protein 7
    • P-glycoprotein 7
    • PGP7
    see all
  • 機能
    Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
  • 関連疾患
    Defects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
  • 配列類似性
    Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • 細胞内局在
    Mitochondrion inner membrane.
  • Information by UniProt

参考文献

ab66358 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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