製品の概要

  • 製品名Anti-HUCE1 antibody
    HUCE1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to HUCE1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human HUCE1 (NP_056139.1)

  • ポジティブ・コントロール
    • HeLa cell lysate, HUCE1 transfected 293T cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab89478 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa.

ターゲット情報

  • 機能Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
  • 配列類似性Belongs to the methyltransferase superfamily. RRP8 family.
  • 細胞内局在Nucleus > nucleolus. Localizes at rDNA locus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cerebral protein 1 antibody
    • hypothetical protein LOC23378 antibody
    • KIAA0409 antibody
    • Nucleomethylin antibody
    • Ribosomal RNA processing 8 methyltransferase homolog antibody
    • Ribosomal RNA processing 8, methyltransferase, homolog (yeast) antibody
    • Ribosomal RNA processing protein 8 antibody
    • Ribosomal RNA-processing protein 8 antibody
    • RRP 8 antibody
    • RRP8 antibody
    • RRP8 methyltransferase homolog antibody
    • RRP8_HUMAN antibody
    see all

Anti-HUCE1 antibody 画像

Anti-HUCE1 antibody (ab89478) 使用論文

ab89478 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"