製品の概要

  • 製品名
    HU-331
  • 製品の詳細
    Potent cannabinoid quinone. Topoisomerase II inhibitor.
  • 生理活性の詳細
    Potent cannabinoid quinone (EC50 = 0.2 μg/ml) with antineoplastic activity; antitumoriogenic and antiangiogenic in vitro and in vivo. Highly specific inhibitor of topoisomerase II.
  • 精製度
    > 95%

製品の特性

参考文献

This product has been referenced in:
  • Kogan NM  et al. HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor. Mol Cancer Ther 6:173-83 (2007). Read more (PubMed: 17237277) »
  • Kogan NM  et al. A cannabinoid anticancer quinone, HU-331, is more potent and less cardiotoxic than doxorubicin: a comparative in vivo study. J Pharmacol Exp Ther 322:646-53 (2007). Read more (PubMed: 17478614) »
  • Kogan NM  et al. Synthesis and antitumor activity of quinonoid derivatives of cannabinoids. J Med Chem 47:3800-6 (2004). Read more (PubMed: 15239658) »

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