Anti-HtrA3 抗体 - Catalytic domain (ab65911)
Key features and details
- Rabbit polyclonal to HtrA3 - Catalytic domain
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-HtrA3 antibody - Catalytic domain
HtrA3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HtrA3 - Catalytic domain -
由来種
Rabbit -
特異性
ab65911 recognizes both of the isoforms of HtrA3. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide based on the catalytic domain of human HtrA3.
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ポジティブ・コントロール
- Extracts of SW 620 in Serum Free, or treated with TPA, IL 1-Alpha, or IL 1-Beta.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: PBS, 50% Glycerol, 2.9% Sodium chloride -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab65911の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
特記事項 |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Probable serine protease. -
組織特異性
Widely expressed, with highest levels in both adult and fetal heart, ovary, uterus placenta, and bladder. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney. -
配列類似性
Belongs to the peptidase S1B family.
Contains 1 IGFBP N-terminal domain.
Contains 1 Kazal-like domain.
Contains 1 PDZ (DHR) domain. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 94031 Human
- Omim: 608785 Human
- SwissProt: P83110 Human
- Unigene: 479119 Human
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別名
- High temperature requirement factor A3 antibody
- High-temperature requirement factor A3 antibody
- HtrA serine peptidase 3 antibody
see all
画像
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All lanes : Anti-HtrA3 antibody - Catalytic domain (ab65911) at 1/1000 dilution
Lane 1 : SW 620 with SF
Lane 2 : SW 620 with TPA
Lane 3 : SW 620 with IL 1-Alpha
Lane 4 : SW 620 with IL 1-Beta
Lane 5 : Molecular weight markers
Predicted band size: 50 , 38 kDa
Observed band size: 40,48 kDa why is the actual band size different from the predicted?
Multiple additonal bands are observed. We are unsure as to the identity of these extra bands.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab65911 は 1 報の論文で使用されています。
- Russell TM & Johnson BJ Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity. Mol Microbiol 90:228-40 (2013). PubMed: 23710801