製品の概要

  • 製品名
    Anti-HTR12 antibody
  • 製品の詳細
    Rabbit polyclonal to HTR12
  • アプリケーション
    適用あり: ICC, WBmore details
  • 種交差性
    交差種: Arabidopsis thaliana
  • 免疫原

    Synthetic peptide derived from the N terminal domain of Arabidopsis thaliana HTR12

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: Whole serum
  • 精製度
    Whole antiserum
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab72001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent dilution.
WB 1/200 - 1/2000. Predicted molecular weight: 20 kDa.

ターゲット情報

  • 関連性
    HTR12 is a histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation and may serve as an epigenetic mark that propagates centromere identity through replication and cell division.
  • 細胞内局在
    Nucleus. Centromere. Kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres.
  • 参照データベース
    • 別名
      • CENH3 antibody
      • Centromeric histone CENH3 antibody
      • F6F3.17 antibody
      • F6F3_17 antibody
      • Histone H3 like centromeric protein HTR12 antibody
      • HTR 12 antibody
      see all

    参考文献

    This product has been referenced in:
    • Karimi-Ashtiyani R  et al. Point mutation impairs centromeric CENH3 loading and induces haploid plants. Proc Natl Acad Sci U S A 112:11211-6 (2015). WB . Read more (PubMed: 26294252) »
    • Mérai Z  et al. The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes. Proc Natl Acad Sci U S A 111:16166-71 (2014). Read more (PubMed: 25344531) »

    See all 2 Publications for this product

    レビューと Q&A


    Unfortunately the immunogen sequence is considered proprietary (commercially sensitive and confidential) and I can not disclose it at this time. However, I can confirm that the immunogen is a peptide of 20 amino acids located between 1 and 40 amin...

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    Thank you very much for contacting us with your question.

    Unfortunately the immunogen sequence is considered commercially sensitive and we can not disclose it at this time. I can onlyconfirm that it is taken from the first 100 N-terminal amin...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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