Anti-HTLV I gp46 抗体 [65/6C2.2.34] (ab9086)

製品の概要

  • 製品名
    Anti-HTLV I gp46 antibody [65/6C2.2.34]
    HTLV I gp46 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [65/6C2.2.34] to HTLV I gp46
  • 特異性
    Human T-Lymphotropic Virus Type I (HTLV I) surface protein, gp46 and with MTA-4 recombinant HTLV I env. Reacts with formalin fixed tissue. Cross-reactivity with the surface protein HTLV II (moT) has been observed.
  • アプリケーション
    適用あり: WB, Radioimmunoprecipitation, ELISA, ICC/IFmore details
  • 免疫原

    Synthetic peptide corresponding to HTLV I gp46 aa 210-306.

  • エピトープ
    The epitope is located between amino acids 210-306 of the viral env gene.
  • 特記事項

    The antibody is used to detect HTLV I surface protein and its precursor in lysates prepared from virons or infected cells. Using immunoblotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may be studied.

    Antibody dilutions should be prepared using buffers containing suitable protein in order to stabilize antibody activity.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Ammonium Sulphate Precipitation
  • 特記事項(精製)
    Purified from serum-free culture supernatant. The antibody is greater than 85% pure as determined using denaturing polyacrylamide gel electrophoresis.
  • 一次抗体 備考
    The antibody is used to detect HTLV I surface protein and its precursor in lysates prepared from virons or infected cells. Using immunoblotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may be studied.
  • ポリ/モノ
    モノクローナル
  • クローン名
    65/6C2.2.34
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab9086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 10 µg/ml.
Radioimmunoprecipitation Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
ICC/IF Use a concentration of 1 - 10 µg/ml.

ターゲット情報

  • 関連性
    HTLV I gp46 surface protein is processed from its precursor gp62. It attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane.
  • 細胞内局在
    Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein
  • 別名
    • Glycoprotein 46 antibody
    • SU antibody
    • Surface protein antibody

参考文献

ab9086 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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