製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPhosphate buffered saline
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名2C10
  • ミエローマNS1/1-Ag4-1
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab6507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000.
ELISA 1/102400.
ICC/IF 1/3200 - 1/25600.

1/3,200 (HSV-2) - 1/25,600 (HSV-1).

ターゲット情報

  • 関連性Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans. They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. Under a microscope, HSV- 1 and 2 are virtually identical, sharing approximately 50% of their DNA. Both types infect the body's mucosal surfaces, usually the mouth or genitals, and then establish latency in the nervous system. HSV-1 is commonly associated with herpes outbreaks of the face known as cold sores or fever blisters, whereas HSV-2 is more often associated with genital herpes. Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
  • 別名
    • Envelope glycoprotein D antibody
    • GD antibody
    • Glycoprotein D antibody
    • US6 antibody

Anti-HSV1 + HSV2 gD antibody [2C10] 画像

Anti-HSV1 + HSV2 gD antibody [2C10] (ab6507) 使用論文

This product has been referenced in:
  • Çuburu N  et al. Topical herpes simplex virus 2 (HSV-2) vaccination with human papillomavirus vectors expressing gB/gD ectodomains induces genital-tissue-resident memory CD8+ T cells and reduces genital disease and viral shedding after HSV-2 challenge. J Virol 89:83-96 (2015). WB . Read more (PubMed: 25320297) »
  • Abe T & Barber GN Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-?B activation through TBK1. J Virol 88:5328-41 (2014). Read more (PubMed: 24600004) »

See all 7 Publications for this product

Product Wall

I am sorry to hear that you have been experiencing problems using this product in the application that you wish.

In order to assess the quality of our products I would ask that you complete a brief questionnaire relating to the application us...

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Thank you for providing these details. When this antibody was characterized in Western blotting with HSV-1 Antigen and the HSV-2 Infected Cell Extract, the antibody worked at dilutions from 1:10,000-1:80,000. As you're seeing a very weak signal using a...

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Thank you for your enquiry. I was able to obtain the following information from our source for this antibody about how it was tested in Western blotting. Ab6507 was tested using the HSV-1 Antigen and the HSV-2 Infected Cell Extract at 10 micrograms/cm....

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Thank you for your e-mail and congratulations on your paper. I can certainly arrange a refund on your recent order of ab6507 if the antibody was purchased in the last 90days and if you could provide your order details. We have not received any other...

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I assume that you are doing frozen section work. 100% acetone for 10 minutes is usually a good fixative for this purpose. Aside, use PBS to dilute the antibody and for washes.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"