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RabMAb

Anti-Hsp105 抗体 [EPR4577] (ab108625)

製品の概要

  • 製品名
    Anti-Hsp105 antibody [EPR4577]
    Hsp105 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4577] to Hsp105
  • アプリケーション
    適用あり: WB, IP, IHC-P, ICC/IFmore details
    適用なし: Flow Cyt
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Hsp105.

  • ポジティブ・コントロール
    • HeLa and HepG2 cell lysates; Human testis tissue; HeLa cells.
  • 特記事項

    A trial size is available to purchase for this antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    EPR4577
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab108625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000 - 1/50000. Predicted molecular weight: 97 kDa.
IP 1/10 - 1/100.
IHC-P 1/100 - 1/250. Antigen retrieval is recommended.
ICC/IF 1/100 - 1/250.
  • 追加情報
    Is unsuitable for Flow Cyt.
  • ターゲット情報

    • 機能
      Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
    • 組織特異性
      Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
    • 配列類似性
      Belongs to the heat shock protein 70 family.
    • 翻訳後修飾
      Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
    • 細胞内局在
      Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Antigen NY CO 25 antibody
      • Antigen NY-CO-25 antibody
      • DKFZp686M05240 antibody
      • Heat shock 105kD alpha antibody
      • Heat shock 105kD antibody
      • Heat shock 105kD beta antibody
      • Heat shock 105kDa protein 1 antibody
      • Heat shock 105kDa protein antibody
      • Heat shock 105kDa/110kDa protein 1 antibody
      • Heat shock 110 kDa protein antibody
      • Heat shock 110kDa protein antibody
      • Heat shock protein 105 kDa antibody
      • HS105_HUMAN antibody
      • HSP105 antibody
      • HSP105A antibody
      • HSP105B antibody
      • HSP110 antibody
      • HSPH 1 antibody
      • Hsph1 antibody
      • KIAA0201 antibody
      • NY CO 25 antibody
      see all

    画像

    • All lanes : Anti-Hsp105 antibody [EPR4577] (ab108625) at 1/10000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HepG2 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 97 kDa
    • ab108625 at 1/100 dilution staining Hsp105 in Human testis by Immunohistochemistry, Paraffin-embedded tissue.
    • ab108625 at 1/100 dilution staining Hsp105 in HeLa cells by Immunofluorescence.

    参考文献

    ab108625 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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