製品の概要

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Store in the dark. Avoid repeated freeze / thaw cycles.
  • バッファー
    Constituents: ddH20
  • Concentration information loading...
  • 研究分野
  • 機能
    Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.
  • 配列類似性
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • 翻訳後修飾
    Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function.
    Ubiquitinated on the N-terminus; which is required for proteasomal degradation.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 別名
    • bHLHc1
    • Class C basic helix-loop-helix protein 1
    • MYF 3
    • Myf-3
    • MYF3
    • Myoblast determination protein 1
    • MYOD
    • Myod 1
    • MYOD1
    • MYOD1_HUMAN
    • Myogenic differentiation 1
    • Myogenic factor 3
    • Myogenic factor MYF 3
    • Myogenin D1
    • PUM
    see all

アプリケーション

Our Abpromise guarantee covers the use of ab83599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Real Time PCR Use at an assay dependent dilution. Suitable for the analysis of chromatin immunoprecipitated DNA using Taqman® real time PCR. The probe is labelled with FAM/TAMRA. Quantity provided for 200 reactions. Please see the protocol page for the instructions for this product.

参考文献

ab83599 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Questions for ab83599.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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