Anti-HSD3B1 抗体 (ab65156)
Key features and details
- Rabbit polyclonal to HSD3B1
- Suitable for: ELISA
- Reacts with: Mouse
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-HSD3B1 antibody
HSD3B1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HSD3B1 -
由来種
Rabbit -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab65156の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
ターゲット情報
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機能
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone. -
組織特異性
Placenta and skin. Predominantly expressed in mammary gland tissue. -
パスウェイ
Lipid metabolism; steroid biosynthesis. -
配列類似性
Belongs to the 3-beta-HSD family. -
細胞内局在
Endoplasmic reticulum membrane. Mitochondrion membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 15492 Mouse
- Entrez Gene: 15494 Mouse
- Entrez Gene: 29632 Rat
- Entrez Gene: 360348 Rat
- Entrez Gene: 682974 Rat
- SwissProt: O35469 Mouse
- SwissProt: P24815 Mouse
- SwissProt: P26149 Mouse
see all -
別名
- 3 beta and steroid delta isomerase 1 antibody
- 3 beta and steroid hydroxy delta 5 steroid dehydrogenase antibody
- 3 beta HSD I antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (16)
ab65156 は 16 報の論文で使用されています。
- Ikeda Y et al. The conditional deletion of steroidogenic factor 1 (Nr5a1) in Sox9-Cre mice compromises testis differentiation. Sci Rep 11:4486 (2021). PubMed: 33627800
- Bai J et al. Discovery of methylpyrimidine ring-fused diterpenoid analogs as a novel testosterone synthesis promoter. RSC Adv 9:9709-9717 (2019). PubMed: 35520707
- Bai J et al. Synthesis and biological evaluation of methylpyrimidine-fused tricyclic diterpene analogs as novel oral anti-late-onset hypogonadism agents. Eur J Med Chem 176:21-40 (2019). PubMed: 31091478
- Yang Q et al. Effects of Exposure to Bisphenol A during Pregnancy on the Pup Testis Function. Int J Endocrinol 2019:6785289 (2019). PubMed: 31263496
- Shi X & Fu L Piceatannol inhibits oxidative stress through modification of Nrf2-signaling pathway in testes and attenuates spermatogenesis and steroidogenesis in rats exposed to cadmium during adulthood. Drug Des Devel Ther 13:2811-2824 (2019). PubMed: 31496657