製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to HSD3B1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cynomolgus monkey, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-DRHKETLKSKTQ

    , corresponding to C terminal amino acids 364-375 of Human HSD3B1

  • ポジティブ・コントロール
    • Human Placenta lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab48018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.01 - 0.1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

ターゲット情報

  • 機能
    3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
  • 組織特異性
    Placenta and skin. Predominantly expressed in mammary gland tissue.
  • パスウェイ
    Lipid metabolism; steroid biosynthesis.
  • 配列類似性
    Belongs to the 3-beta-HSD family.
  • 細胞内局在
    Endoplasmic reticulum membrane. Mitochondrion membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3 beta and steroid delta isomerase 1 antibody
    • 3 beta and steroid hydroxy delta 5 steroid dehydrogenase antibody
    • 3 beta HSD I antibody
    • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I antibody
    • 3-beta-HSD I antibody
    • 3-beta-hydroxy-5-ene steroid dehydrogenase antibody
    • 3BETAHSD antibody
    • 3BH antibody
    • 3BHS1_HUMAN antibody
    • 3BHSD antibody
    • Delta-5-3-ketosteroid isomerase antibody
    • HGNC:5217 antibody
    • HSD3B antibody
    • HSD3B1 antibody
    • HSDB3 antibody
    • HSDB3A antibody
    • Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1 antibody
    • Hydroxy delta 5 steroid dehydrogenase antibody
    • Progesterone reductase antibody
    • SDR11E1 antibody
    • Steroid Delta-isomerase antibody
    • trophoblast antigen antibody
    • Trophoblast antigen FDO161G antibody
    see all

画像

  • Anti-HSD3B1 antibody (ab48018) at 0.01 µg/ml + Human Placenta lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 42 kDa
    Observed band size : 42 kDa

プロトコール

参考文献

ab48018 has not yet been referenced specifically in any publications.

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